Two sample MR report
CBWD1_T Proliferating against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.4792853 | 0.5403459 | 0.4404137 |
| Weighted median | 5 | -0.1428369 | 0.0339292 | 0.0000256 |
| Inverse variance weighted | 5 | -0.1267566 | 0.0254594 | 0.0000006 |
| Simple mode | 5 | -0.1487270 | 0.0453950 | 0.0306074 |
| Weighted mode | 5 | -0.1487270 | 0.0472769 | 0.0346514 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1768966 | 3 | 0.9812299 |
| Inverse variance weighted | 1.4376403 | 4 | 0.8376273 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.3388562 | 0.301788 | 0.3432631 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 4.48e-05 | 0 | TRUE | 0.5320408 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
